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As used herein "percent （%） amino acid sequence identity" and "percent identity" when used with respect to an amino acid sequence （reference polypeptide sequence） is defined as the percentage of amino acid residues in a candidate sequence （e.g. the subject antibody or fragment） that are identical with the amino acid residues in the reference polypeptide sequence after aligning the sequences and introducing gaps if necessary to achieve the maximum percent sequence identity and not considering any conservative substitutions as part of the sequence identity. 31. The chimeric antigen receptor of claim 29 wherein: the VH and VL regions of the antibody or fragment comprise the amino acid sequences set forth in SEQ ID NOs: 11 and 13 respectively; the VH and VL regions of the antibody or fragment comprise the amino acid sequences set forth in SEQ ID NOs: 11 and 14 respectively; the VH and VL regions of the antibody or fragment comprise the amino acid sequences set forth in SEQ ID NOs: 11 and 16 respective |
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